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Acceptance Committment Therapy for adolescents who had previously engaged in at least one crime
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Aggression replacement training for adolescents who had previously engaged in at least one crime
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The Connect Program for adolescents who had previously engaged in at least one crime
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Dialectical Behavioral Therapy for adolescents who had previously engaged in at least one crime
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Functional Family Therapy for adolescents who had previously engaged in at least one crime
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Group cognitive–behavioural therapy for adolescents who had previously engaged in at least one crime
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Cognitive behavioral therapy for adolescents who had previously engaged in at least one crime
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Komet for adolescents who had previously engaged in at least one crime
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Contact family or contact person for adolescents who had previously engaged in at least one crime
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Qualified contact person for adolescents who had previously engaged in at least one crime
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The repulse method for adolescents who had previously engaged in at least one crime
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Community intervention team for adolescents who had previously engaged in at least one crime
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Counseling Interventions for adolescents who had previously engaged in at least one crime
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International Child Development Programme for adolescents who had previously engaged in at least one crime
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Relapse therapy for adolescents who had previously engaged in at least one crime
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Low-arousal approach for adolescents who had previously engaged in at least one crime
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Mediation for adolescents who had previously engaged in at least one crime
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Mentorship for adolescents who had previously engaged in at least one crime
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Motivational interview for adolescents who had previously engaged in at least one crime
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Multidimensional Family Therapy for adolescents who had previously engaged in at least one crime
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Multisystemic Therapy for adolescents who had previously engaged in at least one crime regarding reoffence, internalizing behavior and school achievement
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Psychodynamic therapy for adolescents who had previously engaged in at least one crime
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Bariatric surgery for lipedema
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Methods to diagnose lipedema
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Liposuction of affected tissue in lipedema
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Non-surgical treatments for lipedema
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Grenz rays therapy compared to surgery for patients with lentigo maligna melanoma (LMM)
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Grenz rays therapy compared to surgery for patients with lentigo maligna (LM)
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Automated versus manual preparation systems for intravenous drugs in hospitals
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Baclofen treatment (intrathecal or peroral) of hereditary or idiopathic dystonia in children
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Salt therapy for treatment of umbilical granuloma in infants
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The effect of sclerotherapy on chronic Achilles tendinopathy
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Automated Digital Triage in Primary Care compared to triage through a telephone reception managed by nurses
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Centralized automated drug dispensing systems compared to a manual system for patients admitted to hospitals
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Use of bouffant or hood type headgear compared with surgical skull caps or no hair cover for operating room staff during surgery
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Standardized cancer care pathways
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Preoperative whole body wash with chlorhexidine compared to no instructions prior to clean surgical procedures
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Preoperative whole body wash with chlorhexidine compared to no wash prior to clean surgical procedures
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Preoperative whole body wash with chlorhexidine compared to local wash prior to clean surgical procedures
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Interventions to improve adopted children’s mental and physical health
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Low arousal approach for young people (7–18 years) with externalized behaviour problems
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Endovascular versus surgical arterio-venous fistula creation for hemodialysis
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Rituximab for children with symptoms corresponding to the research condition of PANS/PANDAS with respect to health-related quality of life, level of functioning, and symptoms
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Association between the proportion of registered nurses (skill-mix) in the hospital health care team, and patient mortality or risk for falls or pressure ulcers
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Non-steroidal anti-inflammatory drugs (NSAIDs) as a treatment for vertebrae compression pain in older persons
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Opioids as a treatment for vertebrae compression pain in older persons
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Oxycodone (flexible dose) as a treatment for painful osteoarthritis of the knee in older persons
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Paracetamol as a treatment for vertebrae compression pain in older persons
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Pregabalin compared to pregabalin in combination with duloxetine as a treatment for painful diabetic neuropathy in older persons
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Pregabalin compared to amitryptiline as a treatment for painful diabetic neuropathy in older persons
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Pregabalin compared to duloxetine as a treatment for painful diabetic neuropathy in older persons
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Tapentadol (flexible dose) as a treatment for painful osteoarthritis of the knee in older persons
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Tramadol as a treatment for painful diabetic neuropathy in older persons
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Venlafaxine as a treatment for painful diabetic neuropathy in older persons
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Cognitive behavioural therapy (CBT) for fibromyalgia in adults compared to treatment as usual (TAU) or waiting list
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Assessment methods to identify severe fear of childbirth in pregnant women
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Psychosocial treatment in reducing severe fear of childbirth in pregnant women
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Behavioral activation for mild to moderate depression and anxiety disorder during pregnancy
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Behavioral activation for mild to moderate depression during pregnancy
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Behavioral activation for mild to moderate anxiety disorder during pregnancy
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Interpersonal therapy (IPT) for mild to moderate depression and anxiety disorder during pregnancy
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Interpersonal therapy (IPT) for mild to moderate depression during pregnancy
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Interpersonal therapy (IPT) for mild to moderate anxiety disorder during pregnancy
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Cognitive behavioral therapy (CBT) for mild to moderate depression and anxiety disorder during pregnancy
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Cognitive behavioral therapy (CBT) for mild to moderate anxiety disorder during pregnancy
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Mindfulness for mild to moderate depression during pregnancy
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Mindfulness for mild to moderate depression and anxiety disorder during pregnancy
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Mindfulness for mild to moderate anxiety disorder during pregnancy
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Psychodynamic therapy (PDT) for mild to moderate depression and anxiety disorder during pregnancy
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Psychodynamic therapy (PDT) for mild to moderate depression during pregnancy
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Higher compared to lower relational continuity of care for persons with asthma or chronic obstructive pulmonary disease (COPD) regarding adherence to prescribed medication, experience of participation in care and self-management of the disease
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Higher compared to lower relational continuity of care for persons with severe mental illness/severe mental disorder regarding hospitalisation, symptoms and functioning, and adherence to prescribed medication
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Diets for gestational diabetes
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Psychodynamic therapy (PDT) for mild to moderate anxiety disorder during pregnancy
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Counselling for mild to moderate depression and anxiety disorder during pregnancy
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Counselling for mild to moderate depression during pregnancy
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Counselling for mild to moderate anxiety disorder during pregnancy
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Psychological treatment in Psychogenic Non-Epileptic Seizures (PNES)
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Divorce mediation for parents in child custody disputes
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Risk assessment in predicting abuse and neglect of children within the family
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Social and psychological treatment in compulsory treatment of girls
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Bekymringssamtal for adolescents who had previously engaged in at least one crime
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ADAD (Adolescent Drug Abuse Diagnosis) assessment tool for adolescents with substance abuse and social problems
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The 5–15 form for assessing the development and behaviour of children and adolescents from 5 to 15 years of age
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ADDIS-Y (Alcohol Drug Diagnosis Instrument) to diagnose harmful use, abuse and dependence on alcohol and other drugs in adolescents
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CAGE (Cut-down, Annoyment, Guilt Eyeopener) for identification of risky alcohol habits
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DUDIT (Drug Use Disorders Identification Test) for identification of drug-related problems in adolescents
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Standardized assessment methods for assessing the quality of life of children and adolescents
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Mm-MAST (Malmö modification of the Brief Michigan Alcoholism Screening Test) for identification of people with alcohol problems in the general population or in a clinical situation (short version of the screening form MAST)
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NODS (National Opinion Research Center DSM-IV Screen for Gambling) to measure gambling problems
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ORS (Outcome Rating Scale) in assessments of a client's perceptions of problems and goal attainment during therapeutic treatment
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PGSI (Problem Gambling Severity Index) for measuring the prevalence of gambling problems
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PPGM (Problem and Pathological Gambling Measure) for measuring problem and pathological gambling in young adults during last year
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SCL 90 (Symptoms Checklist) in measuring a person’s psychological and physical distress during the past week
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SRS (Session Rating Scale) in measuring the client's perception of a completed treatment interview
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TLFB (Timeline Follow-Back) for identification of increased alcohol consumption among different risk groups
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UngDOK (Documentation system in substance abuse care) in investigations of adolescents with substance abuse and social problems
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AUDIT (Alcohol Use Disorders Identification Test) for identification of risky and harmful alcohol consumption in adolescents
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ASSIST-Y (Alcohol, Smoking and Substance Involvement Sreening Test – Youth) for early identification of the use of unhealthy and harmful substances in children and adolescents
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CBCL (Child Behaviour Check List) to describe problems and social skills in children and adolescents with mental health problems
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CRAFFT (Car, Relax, Alone, Forget, Friends, Trouble) for screening of substance (alcohol or other drugs) based on context and negative consequences (in adolescents)
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CTQ (Childhood Trauma Questionnaire) measuring exposure to violence, sexual abuse and neglect, retrospectively (in adolescents and young adults)
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Intensive lifestyle treatment with low-fat diet compared to regular dietary treatments in type 1 diabetes
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Intensive lifestyle treatment, combining low-fat diet with physical activity, compared to regular dietary treatments in type 1 diabetes
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Intensive lifestyle treatments with a high-protein diet (20E%) combined with physical activity, compared to regular dietary treatments in type 1 diabetes
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Intensive lifestyle treatments with reduced energy intake compared to regular dietary treatments in diabetes type 1
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Intensive lifestyle treatments with a ketogenic diet compared to regular dietary treatments in type 1 diabetes
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Intermittent energy intake restriction compared to continuous energy intake restriction in type 1 diabetes
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The weight watchers’ program compared to regular dietary treatments in type 1 diabetes
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Carbohydrate counting compared to plate method in type 1 diabetes
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Advanced carbohydrate counting compared to calculating insulin dose in type 1 diabetes
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Reduced energy diet, in combination with meal replacement based on Very Low Energy Diet (VLED), compared to reduced energy diet in type 1 diabetes
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Meal replacement based on Very Low Energy Diet (VLED) compared to low fat diet in type 1 diabetes
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Buprenorphine compared to placebo as a treatment for painful diabetic neuropathy in older persons
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Capsaicin cream 0,075% as a treatment for painful diabetic neuropathy in older persons
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Intensive lifestyle treatments with reduced energy diet compared to regular dietary treatments in diabetes type 2
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Intermittent energy intake restriction compared to continuous energy intake restriction in type 2 diabetes
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Carbohydrate counting compared to plate method in type 2 diabetes
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Reduced energy diet, in combination with meal replacement based on Very Low Energy Diet (VLED), compared to reduced energy diet in type 2 diabetes
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Diclofenac (flexible dose) compared to paracetamol (flexible dose) as a treatment for painful osteoarthritis of the knee in older persons
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Duloxetine 60 mg x2 compared to duloxetine 120 mg as a treatment for painful diabetic neuropathy in older persons
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High-protein diet (20 E%) compared to low-fat diet in type 1 diabetes
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High-protein diet (30 E%) compared to low-fat diet in type 1 diabetes
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High-protein diet 30 E% compared to high-protein diet 20 E% in type 1 diabetes
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Low-carb diet compared to low-fat diet in type 1 diabetes
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Low-carb diet, without energy restrictions, compared to low-fat diet in type 1 diabetes
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Duloxetine compared to duloxetine in combination with pregabalin as a treatment for painful diabetic neuropathy in older persons
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Ketogenic diet, with or without energy restrictions, compared to low-fat diet, with or without energy restrictions, in type 1 diabetes
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Ketogenic diet without energy restrictions compared to low-fat diet with energy restrictions in type 1 diabetes
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Ketogenic diet compared to low-fat diet in type 1 diabetes
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Gabapentin compared to gabapentin in combination with nortriptyline as a treatment for painful diabetic neuropathy in older persons
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Mediterranean diet compared to low-fat diet in type 1 diabetes
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Diet with low glycemic index (GI) compared to diet with high GI in type 1 diabetes
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Vegetarian diet compared to low-fat diet in type 1 diabetes
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Ornish diet compared to low-fat diet with energy restrictions in type 1 diabetes
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Energy reduced diet, with or without the addition of physical activity, compared to regular dietary treatments in type 1 diabetes
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High-protein diet (20 E%) compared to low-fat diet in type 2 diabetes
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High-protein diet (30 E%) compared to low-fat diet in type 2 diabetes
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High-protein diet 30 E% compared to high-protein diet 20 E% in type 2 diabetes
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Low-carb diet compared to low-fat diet in type 2 diabetes
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Low-carb diet, without energy restrictions, compared to low-fat diet in type 2 diabetes
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Gabapentin compared to nortriptyline as a treatment for painful diabetic neuropathy in older persons
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Ketogenic diet, with or without energy restrictions, compared to low-fat diet, with or without energy restrictions, in type 2 diabetes
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Ketogenic diet without energy restrictions compared to low-fat diet with energy restrictions in type 2 diabetes
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Ketogenic diet compared to low-fat diet in type 2 diabetes
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Surgical interventions for women with symptomatic diastasis recti
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Physiotherapeutic interventions for women with symptomatic diastasis recti
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Capsaicin cream compared to amitryptiline as a treatment for painful diabetic neuropathy in older persons
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Diet with low glycemic index (GI) compared to diet with high GI in type 2 diabetes
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Topical ketoprofen as a treatment for painful osteoarthritis of the knee in older persons
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Vegetarian diet compared to low-fat diet in type 2 diabetes
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Ornish diet compared to low-fat diet with energy restrictions in type 2 diabetes
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Higher compared to lower consumption of paleolithic diet in type 1 diabetes
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Higher compared to lower consumption of protein in type 1 diabetes
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Higher compared to lower consumption of Dietary Approach to Stop Hypertension (DASH) in type 1 diabetes
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Higher compared to lower consumption of paleolithic diet in type 2 diabetes
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Higher compared to lower consumption of Dietary Approach to Stop Hypertension (DASH) in type 2 diabetes
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Higher compared to lower consumption of protein in type 2 diabetes
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Lacosamide as a treatment for painful diabetic neuropathy in older persons
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Lidocaine patch 5% compared to pregabalin as a treatment for painful diabetic neuropathy in older persons
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Nortriptyline compared to gabapentin in combination with nortriptyline as a treatment for painful diabetic neuropathy in older persons
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Individual Placement and Support (IPS) intervention for persons on long-term sick leave for depression, anxiety or reaction to severe stress
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Preparatory programs in the form of support and capital to start your own business for long-term social assistance recipients
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Preparatory program in the form of individual support and work-training for long-term social assistance recipients
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Post-suicide intervention in schools and preschools
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Virtual Reality in the treatment of eating disorders
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Safewards to reduce coercive measures in forensic psychiatric care
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Six core strategies to reduce coercive measures in inpatient mental healthcare, including compulsory psychiatric care and forensic psychiatric care
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Water compared to beverages that contain sweeteners in type 2 diabetes
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Higher compared to lower consumption of fish in type 1 diabetes
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Higher compared to lower consumption of eggs in type 1 diabetes
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Higher compared to lower consumption of fruit in type 1 diabetes
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Higher compared to lower consumption of salt in type 1 diabetes
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Higher compared to lower consumption of fat (regardless of type) in type 1 diabetes
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Higher compared to lower consumption of animal fat in type 1 diabetes
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Higher compared to lower consumption of vegetable fat in type 2 diabetes
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Higher compared to lower consumption of polyunsaturated fat in type 2 diabetes
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Higher compared to lower consumption of trans fat in type 2 diabetes
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Higher compared to lower consumption of omega-3 fatty acids from fish and seafood in type 2 diabetes
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Higher compared to lower consumption of the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in type 2 diabetes
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Higher compared to lower consumption of cholesterol in type 2 diabetes
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Higher compared to lower consumption of vegetable fat in type 1 diabetes
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Higher compared to lower consumption of saturated fat in type 1 diabetes
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Higher compared to lower consumption of polyunsaturated fat in type 1 diabetes
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Higher compared to lower consumption of trans fat in type 1 diabetes
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Higher compared to lower consumption of omega-3 fatty acids from fish and seafood in type 1 diabetes
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Higher compared to lower consumption of the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in type 1 diabetes
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Higher compared to lower consumption of cholesterol in type 1 diabetes
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Higher compared to lower consumption of tea in type 1 diabetes
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Higher compared to lower consumption of green tea in type 1 diabetes
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Higher compared to lower consumption of peanuts in type 1 diabetes
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Higher compared to lower consumption of fish in type 2 diabetes
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Higher compared to lower consumption of eggs in type 2 diabetes
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Higher compared to lower consumption of fruit in type 2 diabetes
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Higher compared to lower consumption of salt in type 2 diabetes
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Higher compared to lower consumption of fat (regardless of type) in type 2 diabetes
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Higher compared to lower consumption of animal fat in type 2 diabetes
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Higher compared to lower consumption of tea in type 2 diabetes
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Higher compared to lower consumption of green tea in type 2 diabetes
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Higher compared to lower consumption of peanuts in type 2 diabetes
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Focused Acceptance and Commitment Therapy (FACT) compared to traditional CBT, ACT, or another active treatment in depression
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Focused Acceptance and Commitment Therapy (FACT) compared to traditional CBT, ACT, or another active treatment in anxiety disorder
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Access to an electric wheelchair for indoor use and another electric wheelchair for outdoor use, compared to access to one electric wheelchair only (for both indoor and outdoor use)
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Access to both manual wheelchair and electric wheelchair compared to access to manual wheelchair only
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Wheelchair with individual adaptations compared to wheelchair without individual adaptations
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Practical education and training in the use of a wheelchair, compared to no practical training and education or only theoretical information or instruction
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Freedom to be able to choose a wheelchair and additional equipment (freedom of choice) compared to lack of choice
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Comparison between different variants of electric wheelchairs
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Access to both manual wheelchair and wheelchair scooter compared to access to manual wheelchair only
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Access to both manual wheelchair for activities in the full range of life situations and manual wheelchair for recreational activities compared to access only to manual wheelchair for activities in life situations
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Wheelchair with person-specific molded seat unit compared to wheelchair without person-specific molded seat unit
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Individually adapted wheelchair seat cushions compared to seat cushions that are not individually adapted
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Propulsion units for manual wheelchairs compared to manual wheelchairs without propulsion units
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Hand-propelled devices added to a manual wheelchair to transform it into a handbike (half-handbike) compared to manual wheelchair without such devices
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Exemption from fees compared to fees for wheelchairs and additional equipment
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Manual wheelchair with wheels in heavier or less stiff material compared to wheels in lighter or more stiff material
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Lightweight manual wheelchair compared to manual wheelchair in a heavier material
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Manual wheelchair with suspension or vibration attenuation compared to manual wheelchair without suspension or vibration attenuation
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Allograft compared to conventional treatment in peripheral nerve surgery
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Endoscope-assisted coblation compared to conventional curettage for patients with Osler disease
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Endoscope-assisted coblation compared to conventional curettage for patients with inverted papilloma
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Acupressure compared to placebo in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Acupuncture compared to placebo in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Initial fasting compared to expedited oral intake in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Granisetron compared to promethazine in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Holistic individual care plan in addition to standard care compared to standard care alone in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Hydrocortisone compared to metoclopramide in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Ginger capsules compared to placebo in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Ondansetron combined with metoclopramide compared to monotherapy or placebo in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Metoclopramide compared to promethazine in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Ondansetron compared to metoclopramide in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Ondansetron compared to promethazine in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Prednisolone compared to placebo in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Dextrose saline compared to normal saline rehydration in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Nasogastric tube feeding in addition to standard care compared to standard care alone in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Vitamin B6 compared to placebo in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Outpatient compared to inpatient care in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Promethazine in combination with ephedrine and caffeine compared to placebo in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Psychological treatment in extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Psychosocial support in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Sick leave in extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Total parenteral nutrition (TPN) in addition to standard care compared to standard care alone in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)
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Specific devices for expiratory muscle strength training (EMST) in patients with multiple sclerosis (MS)
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Specific devices for expiratory muscle strength training (EMST) in patients with Parkinson’s disease (PD)
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Blood group matching with genotyping
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Innowalk for children and young people with mobility impairments
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High-fat diet, including greater consumption of dairy products, compared to the same treatment as the intervention group but with a maintained baseline dairy intake in type 1 diabetes
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Water compared to beverages that contain sweeteners in type 1 diabetes
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High-fat diet, including greater consumption of dairy products, compared to the same treatment as the intervention group but with a maintained baseline dairy intake in type 2 diabetes
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Osseointegrated upper limb prostheses with and without neuromuscular control
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Rezum compared to minimal invasive surgical treatment (MIST) as a treatment for symptomatic prostate enlargement
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Rezum compared to transurethral resection of the prostate (TURP) as a treatment for symptomatic prostate enlargement
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Physiotherapy via digital contact in comparison with in-house mediated physiotherapy for patients diagnosed with osteoarthritis (OA) of the knee or hip
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Mobile applications for monitoring and feedback in asthma and chronic obstructive pulmonary disease (COPD)
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Mobile health applications for monitoring and feedback in cronic heart failure
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Concern calls to reduce gun violence among criminal street gangs
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Community Initiative to Reduce Violence (CIRV) among criminal street gangs
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Drug market intervention (DMI) to prevent gun violence
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Family-based therapy for delinquent youth with a known gang affiliation or high gang risk
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Psychosocial interventions during incarceration for individuals affiliated to gangs, in order to prevent relapse in gang-related crime
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Kurve Kriegen to reduce gun violence among criminal street gangs
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Outreach programs to enhance mediation among criminal street gangs
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Operation Peacemaker Fellowship among criminal street gangs
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Police-Led Community Initiative to Reduce Gun violence among criminal street gangs
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The intervention Repulse to reduce gun violence among criminal street gangs
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Social action groups to reduce gun violence among criminal street gangs
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General supportive bereavement care for parents and siblings of stillborn children
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Support programs, focusing on post-loss care, for parents and siblings of stillborn children
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Support programs, which focuses on facilitating the grieving process, for parents and siblings of stillborn children
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Correlation between perceived work-related stress and temporomandibular disorders in working adults
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Population-based mammography screening for women over the age of 74
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Regular testicular self-examination (TSE) in the general male population to increase early detection of testicular cancer
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Negative Pressure Wound Treatment (NPWT) in healing of chronic wounds
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Long term effects of robot-assisted vs freehand surgery of the spine
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Dynamic braces for non surgical treatment of patients with isolated PCL injuries
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Long-term effects of interpersonal therapy (IPT) during postpartum depression
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Counselling compared to cognitive behavioral therapy (CBT) during postpartum depression
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Interventions to promote parental responsiveness and child development during postpartum depression
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Interpersonal therapy (IPT) compared to cognitive behavioral therapy (CBT) during postpartum depression
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Short-term psychodynamic therapy (short-term PDT) during postpartum depression
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Psychodynamic therapy (PDT) compared to cognitive behavioral therapy (CBT) during postpartum depression
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Medication use for epilepsy prevention after stroke
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Medication use for epilepsy prevention after traumatic brain injury
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A new direction
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The effect of written exposure therapy (WET) on post-traumatic stress disorder
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Measuring anovaginal distance using ultrasound, directly after delivery, to detect damage to the external sphincter
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MRI compared to clinical examination for diagnosing levator injuries after vaginal delivery
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Tomographic ultrasound imaging at maximum pelvic floor muscle contraction compared to at rest for diagnosing levator injuries after vaginal delivery
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Transperineal ultrasound compared to endovaginal ultrasound for diagnosing levator injuries after vaginal delivery
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Ultrasound examination compared to clinical examination for diagnosing levator injuries after vaginal delivery
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Transperineal ultrasound in addition to clinical assessment in the diagnosis of birth injuries after vaginal delivery
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Hypnotherapy compared to other or no treatment in individuals with pain, anxiety disorders, or depression
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Comparison of different types of postoperative dressings without negative pressure in surgical wound healing by primary intention in adults
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Psyllium compared to other treatments in chronic constipation in adults and the elderly
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Methylprednisolone compared to promethazine in the treatment of extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)