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Intermittent cortisone injection for treatment of osteoarthritis and chronic obstructive lung disease

Osteoarthritis and chronic obstructive lung disease (COPD) are conditions where the pharmacological treatment is focused on retardation of disease progression and symptom alleviation. In osteoarthritis, degenerative changes in bone and cartilage of the joints can lead to impaired function and pain. COPD is characterized by the reduction of respiratory capacity and lung function, due to degeneration of the alveoli and inflammation of the small bronchi.

Cortisone belongs to a group of pharmaceuticals called glucocorticoids. This compound has been used for more than 50 years to treat inflammatory diseases including rheumatoid arthritis and allergy.

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SBU Enquiry Service

Consists of structured literature searches to highlight studies that can address questions received by the SBU Enquiry Service from Swedish healthcare or social service providers. We assess the risk of bias in systematic reviews and when needed also quality and transferability of results in health economic studies. Relevant references are compiled by an SBU staff member, in consultation with an external expert when needed.

Question

Is there any evidence showing that intermittent intramuscular cortisone injection (ICI method) can have beneficial effects on osteoarthritis or COPD?

The complete Enquiry response is published in Swedish. Click on ”På svenska” in the top menu to read it.

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