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Influence of delay on breast cancer surgery outcome

In Sweden as well as worldwide, breast cancer is the most common cancer diagnosis in women, and surgery is the primary treatment for curative care. As the time between diagnosis and surgery can vary substantially, it is essential to know if wait time for operative procedures may influence surgery outcomes.

SBU Enquiry Service

Consists of structured literature searches to highlight studies that can address questions received by the SBU Enquiry Service from Swedish healthcare or social service providers. We assess the risk of bias in systematic reviews and when needed also quality and transferability of results in health economic studies. Relevant references are compiled by an SBU staff member, in consultation with an external expert when needed.

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What systematic reviews are there on surgical wait time and medical outcomes in breast cancer patients?

Identified literature

No relevant systematic reviews with low/medium risk of bias were found.

Published: Report no: ut201926 Registration no: SBU 2019/365

Literature search

PubMed via NLM 190830 
Title: Breast cancer surgery delay
The search result, usually found at the end of the documentation, forms the list of abstracts. [MeSH] = Term from the Medline controlled vocabulary, including terms found below this term in the MeSH hierarchy; [MeSH:NoExp] = Does not include terms found below this term in the MeSH hierarchy; [MAJR] = MeSH Major Topic; [TIAB] = Title or abstract; [TI] = Title; [AU] = Author; [TW] = Text Word; * = Truncation
  Search terms Items found
1. ”Breast Neoplasms"[Mesh]  
2. "Mastectomy"[Mesh]  
3. breast neoplasm[Title/Abstract] OR breast neoplasms[Title/Abstract] OR breast carcinoma[Title/Abstract] OR breast carcinomas[Title/Abstract] OR breast tumour[Title/Abstract] OR breast tumours[Title/Abstract] OR breast tumor[Title/Abstract] OR breast tumors[Title/Abstract] OR breast malignancies[Title/Abstract] OR breast cancer[Title/Abstract]  
4. 1 OR 2 OR 3 362699
5. "Time-to-Treatment"[Mesh]  
6. "Time Factors"[Mesh]  
7. wait time[Title/Abstract] OR waiting time[Title/Abstract] OR wait list[Title/Abstract] OR waiting list[Title/Abstract] OR wait scheme[Title/Abstract] OR treatment delay[Title/Abstract] OR delayed treatment[Title/Abstract] OR time to treatment[Title/Abstract] OR time to therapy[Title/Abstract] OR time to surgery[Title/Abstract] OR time interval[Title/Abstract] OR timeliness[Title/Abstract] OR surgical delay[Title/Abstract] OR delayed surgery[Title/Abstract]  
8. 5 OR 6 OR 7 1205976
Combined sets:
9. 4 AND 8 16519
Study types:
10. ((((systematic review[ti] OR systematic literature review[ti] OR systematic scoping review[ti] OR systematic narrative review[ti] OR systematic qualitative review[ti] OR systematic evidence review[ti] OR systematic quantitative review[ti] OR systematic meta-review[ti] OR systematic critical review[ti] OR systematic mixed studies review[ti] OR systematic mapping review[ti] OR systematic cochrane review[ti] OR systematic search and review[ti] OR systematic integrative review[ti]) NOT comment[pt] NOT (protocol[ti] OR protocols[ti])) NOT MEDLINE[subset]) OR ("Cochrane Database Syst Rev"[Journal] AND review[pt]) OR systematic review[pt]) 137841
Final 9 AND 10 114


Embase via 190830 
Title: Breast cancer surgery delay
/de = Term from the EMTREE controlled vocabulary; /exp= Includes terms found below this term in the EMTREE hierarchy; /mj = Major Topic; :ab = Abstract; :au = Author; :ti = Article Title; :ti,ab = Title or abstract; NEAR/n = Proximity operator; * = Truncation; ’ ’ = Citation Marks; searches for an exact phrase
  Search terms Items found
1. 'breast cancer'/exp  
2. 'mastectomy'/exp  
3. breast NEAR/4 (neoplasm OR cancer OR carcinoma OR tumor OR malignancy)):ab,ti  
4. 1 OR 2 OR 3 566756
5. 'therapy delay'/de  
6. 'time to treatment'/de  
7. 'timeliness'/de  
8. 'time factor'/de  
9. ((wait* NEAR/3 (time OR list OR scheme)):ab,ti) OR 'treatment delay':ab,ti OR 'delayed treatment':ab,ti OR (('time to' NEAR/1 (treatment OR therapy OR surgery)):ab,ti) OR 'time interval':ab,ti OR timeliness:ab,ti OR 'surgical delay':ab,ti OR 'delayed surgery':ab,ti  
10. 5 OR 6 OR 7 OR 8 OR 9 130804
Combined sets:
  4 AND 10 3916
Study types:
11. (metaanaly* OR 'meta analy*' OR (systematic* NEAR/3 (review* OR overview)) OR 'meta analysis'/exp OR 'systematic review'/de) 444720
Final 11 AND 12 141


Scopus via 190830
Title: Breast cancer surgery delay
The search result, usually found at the end of the documentation, forms the list of abstracts. TITLE-ABS-KEY = Title or abstract or keywords; ALL = All fields; PRE/n = "precedes by". The first term in the search must precede the second by a specified number of terms (n). W/n = "within". The terms in the search must be within a specified number of terms (n) in any order.; * = Truncation; “ “ = Citation Marks; searches for an exact phrase; LIMIT-TO (SRCTYPE, "j" = Limit to source type journal; LIMIT-TO (DOCTYPE, "ar" = Limit to document type article; LIMIT-TO (DOCTYPE, "re" = Limit to document type review
  Search terms Items found
1. TITLE-ABS-KEY(mastectomy OR (breast W/3 (neoplasm OR cancer OR carcinoma OR tumor OR malignancy))) 524763
2. TITLE-ABS-KEY((“time to” W/0 (treatment OR therapy OR surgery)) OR (wait W/3 (time OR list OR scheme)) OR “treatment delay*” OR “delayed treatment” OR “surgical delay*” OR “delayed surgery” OR “time interval*” OR timeliness OR “time factor*”) 1182096
Combined sets:
3. 1 AND 2 18418
Study types:
4. TITLE-ABS-KEY(metaanalysis OR “meta analy*” OR (systematic W/3 (review OR overview))) 400632
Final 3 AND 4 384
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