Stem cell transplantation as treatment for children with autism

This document was published more than 2 years ago. The nature of the evidence may have changed.

Stem cell transplantations are performed to treat certain forms of cancer but also to treat some other rarer disorders. Today stem cell clinics advertise stem cell transplantation as a treatment to disorders like autism at high costs. There are however doubts about the efficacy and safety of these treatments.

Question

Which scientific studies have investigated stem cell transplantation as treatment for children with autism?

Identified literature

  1. Chez M, Lepage C, Parise C, Dang-Chu A, Hankins A, Carroll M. Safety and Observations from a Placebo-Controlled, Crossover Study to Assess Use of Autologous Umbilical Cord Blood Stem Cells to Improve Symptoms in Children with Autism. Stem Cells Translational Medicine 2018;7:333-341.
  2. Lv YT, Zhang Y, Liu M, Qiuwaxi JN, Ashwood P, Cho SC, et al. Transplantation of human cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells in autism. J Transl Med 2013;11:196.

SBU Enquiry Service Consists of structured literature searches to highlight studies that can address questions received by the SBU Enquiry Service from Swedish healthcare or social service providers. We assess the risk of bias in systematic reviews and when needed also quality and transferability of results in health economic studies. Relevant references are compiled by an SBU staff member, in consultation with an external expert when needed.

Published: 9/19/2018
Contact SBU: registrator@sbu.se
Report no: ut201827