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Electrochemotherapy in treatment of tumours

Electrochemotherapy is a combination therapy for cancer and consists of electroporation and treatment with cytostatic agents. Electroporation is a method that through an electric field temporarily opens the cell membrane which enhances the cytotoxic effect. Electrochemotherapy is used to a limited extent in Sweden and an essential question is if there is evidence that the method is effective and cost effective in treatment of tumours.

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SBU Enquiry Service

Consists of structured literature searches to highlight studies that can address questions received by the SBU Enquiry Service from Swedish healthcare or social service providers. We assess the risk of bias in systematic reviews and when needed also quality and transferability of results in health economic studies. Relevant references are compiled by an SBU staff member, in consultation with an external expert when needed.

Question

Is there evidence that electrochemotherapy is effective and cost effective in treatment of tumours?

The complete Enquiry response is published in Swedish. Click on ”På svenska” in the top menu to read it.

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Search term(s)

Electroporation Cytostatic agents Tumour Metastasis
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Literature search

Literature search.pdf

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