Electrochemotherapy in treatment of tumours

Electrochemotherapy is a combination therapy for cancer and consists of electroporation and treatment with cytostatic agents. Electroporation is a method that through an electric field temporarily opens the cell membrane which enhances the cytotoxic effect. Electrochemotherapy is used to a limited extent in Sweden and an essential question is if there is evidence that the method is effective and cost effective in treatment of tumours.

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SBU Enquiry Service

Responds to queries received from Swedish healthcare and social service providers, or governmental organisations. Queries have a limited scope and the process is designed to enable a more rapid response, typically within two to three months. Reports are based on systematic reviews, that are identified through structured searches and critically appraised for risk of bias.

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Search term(s)

Electroporation Cytostatic agents Tumour Metastasis

Question

Is there evidence that electrochemotherapy is effective and cost effective in treatment of tumours?

The complete Enquiry response is published in Swedish. Click on ”På svenska” in the top menu to read it.

Literature search

Literature search.pdf

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