Universal cervical length screening of women with singleton pregnancies, followed by progesterone with or without additional treatment for short cervix to prevent preterm birth, compared with no screening

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This page contains 1 evidence gap
  1. Universal cervical length screening of women with singleton pregnancies, followed by progesterone with or without additional treatment for short cervix to prevent preterm birth, compared with no screening
Population:
Women with singleton pregnancies
Intervention:
Screening with transvaginal ultrasound and measurement of cervical length followed by vaginal or oral progesterone, with or without additional treatment, if short cervical length is demonstrated
Comparison:
No screening with transvaginal ultrasound
Outcomes:
Preterm birth, perinatal mortality and morbidity

What evidence is needed?

More primary research is needed.

What evidence is available?

Reliable systematic reviews that show evidence gaps:

Zethelius M, Bergman L, Ekelund A-C, Hongslo Vala C, Jacobsson B, Khan J, Kuusela P, Liljegren A, Petzold M, Sjögren P, Wennerholm U-B, Wikström T, Lindkvist B. Cervical length screening followed by progesterone treatment for short cervix to prevent preterm birth. [Screening av cervixlängd och behandling med progesteron vid kort cervix för att förebygga förtidsbörd]. Göteborg: Västra Götalandsregionen, Sahlgrenska Universitetssjukhuset, HTA-centrum; 2025. Regional activity based HTA 2025:141.
More about the review

Reliable, but not updated, systematic reviews that show evidence gaps:

None identified

Registration number:
Published:
Research conducted after publication could potentially change the nature of the evidence.
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Evidence gap identifies methods or practices for which no conclusive systematic review of benefits and harms has been published. Gaps in scientific evidence appear on the SBU website to help researchers and granting agencies identify areas that are in need of research or systematic review. An additional objective is to offer healthcare and social service providers a basis for setting priorities.