Torkat svinsköldkörtelextrakt vid hypotyreos jämfört med syntetiskt framställt hormon (LT4)

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  1. Torkat svinsköldkörtelextrakt vid hypotyreos jämfört med syntetiskt framställt hormon (LT4)
Population:
Adults ≥ 18 years with hypothyroidism
Intervention:
Desiccated thyroid extract (DTE)
Comparison:
Levothyroxine (L-T4) (or a combination of Levothyroxine + Liothyronine (L-T4 + L-T3))
Outcomes:
Symptoms, clinical findings, quality of life, TSH, T4, T3, side effects

What evidence is needed?

More primary research is needed.

What evidence is available?

Reliable systematic reviews that show evidence gaps:

Henning L, Nousios P, Snellman A, Breimer L, Lohse G, Ahlzén R, Olsson L. Effekt av torkat svinsköldkörtelextrakt vid hypotyreos – en systematisk översikt, förskrivning och hälsoekonomisk analys för Sverige 2017–2021. Örebro: HTA-enheten CAMTÖ; 2023. HTA-rapport 2023: 61.
More about the review

Reliable, but not updated, systematic reviews that show evidence gaps:

None identified

See also SBU Equiry service: SBU. Behandling med en kombination av syntetiska sköldkörtelhormoner (T4 + T3) alternativt sköldkörtelextrakt vid hypotyreos. Stockholm: Statens beredning för medicinsk och social utvärdering (SBU); 2018. SBU:s upplysningstjänst ut201806.
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Evidence gap identifies methods or practices for which no conclusive systematic review of benefits and harms has been published. Gaps in scientific evidence appear on the SBU website to help researchers and granting agencies identify areas that are in need of research or systematic review. An additional objective is to offer healthcare and social service providers a basis for setting priorities.