Radiofrequency or microwave ablation versus surgery for treatment of toxic diffuse autoimmune hyperthyroidism (Graves' disease)

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This page contains 1 evidence gap
  1. Radiofrequency or microwave ablation versus surgery for treatment of toxic diffuse autoimmune hyperthyroidism (Graves' disease)
Population:
Adult patients with toxic diffuse autoimmune hyperthyroidism (Graves' disease), suitable for surgery
Intervention:
Thermal ablation using radiofrequency or microwaves
Comparison:
Surgery (open or endoscopic)
Outcomes:
Health-related quality of life; symptoms change; complications; relapse; malignancy; re-intervention; mortality; operation time (time of surgery); volume reduction; biochemical response; need of hormonal treatment; hospital stay

What evidence is needed?

More primary research is needed.

What evidence is available?

Reliable systematic reviews that show evidence gaps:

Stenlöf K, Bümming P, Dahlberg J, Hammarström A, Jivegård L, Jorna F, Khan J, Petzold M, Stadig I, Svanberg T, Wallén S, Sjögren P.
Radiofrequency or microwave ablation versus surgery for treatment of benign non-toxic or toxic nodules, and toxic diffuse autoimmune hyperthyroidism (Graves' disease).  Göteborg: Västra Götalandsregionen, Sahlgrenska Universitetssjukhuset, HTA-centrum; 2025. Regional activity based HTA 2025:142.
More about the review

Reliable, but not updated, systematic reviews that show evidence gaps:

None identified

Registration number:
Published:
Research conducted after publication could potentially change the nature of the evidence.
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Evidence gap identifies methods or practices for which no conclusive systematic review of benefits and harms has been published. Gaps in scientific evidence appear on the SBU website to help researchers and granting agencies identify areas that are in need of research or systematic review. An additional objective is to offer healthcare and social service providers a basis for setting priorities.