Dental assessment for prevention of medication-related osteonecrosis of the jaw in adults with early breast cancer compared to no dental assessment

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  1. Dental assessment for prevention of medication-related osteonecrosis of the jaw in adults with early breast cancer compared to no dental assessment
Population:
Adult patients with early breast cancer (non-M1; no metastasis) to receive adjuvant bisphosphonate treatment, with or without prior bisphosphonate therapy
Intervention:
Prophylactic dental assessment (with or without oral/dental procedures) before bisphosphonate treatment
Comparison:
No prophylactic dental assessment before bisphosphonate treatment
Outcomes:
Incidence of medication related osteonecrosis of the jaw (MRONJ); mortality; oral health-related quality of life according to validated scales; health-related quality of life according to validated scales; complications; oral health-related symptom scales, validated

What evidence is needed?

More primary research is needed.

Hylén N, Karlsson P, Larsson B, Lund Jacobsen C, Magnusson K, Sjögren P, Stadig I, Hongslo Vala C. Dental assessment for prevention of medicationrelated osteonecrosis of the jaw in adults with early breast cancer [Tandläkarbedömning för prevention av läkemedelsrelaterad käkbensnekros hos vuxna med tidig bröstcancer]. Göteborg: Västra Götalandsregionen, Sahlgrenska Universitetssjukhuset, HTA-centrum: 2025. Regional activity based HTA 2025:146. More about the review

What evidence is available?

Reliable systematic reviews that show evidence gaps:

None identified

Reliable, but not updated, systematic reviews that show evidence gaps:

None identified

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Published:
Research conducted after publication could potentially change the nature of the evidence.
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