Diagnostic accuracy of different index-tests in diagnosing food allergy

Systematic reviews in the field can not clearly distinguish the diagnostic accuracy between different index tests that are used when diagnosing suspected food allergy, at least when an optimal cut-off value for the index test is used.

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"Systematic review and meta-analyses on the accuracy of diagnostic tests for IgE-mediated food allergy” by Riggioni and colleagues, published in the journal Allergy in February 2024 will be discussed in this report [1].

Aim

This report will high-light the complexity of food allergy diagnostics, as well as the available data from Riggioni and colleagues on sensitivity and specificity of different test types for different food allergies.

Project group

Experts

  • David Aronsson, consultant physician, PhD, pulmonary medicine and allergology, Skåne university hospital, Lund university
  • Jon Konradsen, consultant physician, assistant professor, pediatric allergy and pulmonary medicine, Astrid Lindgren's children's hospital, Department of women's and children's health, Karolinska Institutet

From SBU

  • Jonatan Alvan, project manager
  • Jan Holst, Assistant project manager
  • Carl Gornitzki, information specialist
  • Maria Ahlberg, project administrator
  • Jenny Odeberg, head of project

Reference

  1. Riggioni C, Ricci C, Moya B, et al. Systematic review and meta-analyses on the accuracy of diagnostic tests for IgE-mediated food allergy. Allergy. 2024;79:324-352
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