SBU:s upplysningstjänst
Publikation nr: ut202114
Publicerad: 29 juni 2021
Nedladdad: 22 maj 2025
Påverkan på amning av tidig nappanvändning

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Påverkan på amning av tidig nappanvändning

Fråga och sammanfattning

Amning etableras oftast under barnets första levnadsveckor. Det är oklart om napp inverkar negativt på amning under etableringsfasen.

Fråga

Vilka vetenskapliga studier finns om effekten på etablering av amning vid introduktion av napp under de första två levnadsveckorna?

Frågeställare: Socialstyrelsen

Sammanfattning

Tidig introduktion av napp har lyfts fram som en möjlig orsak till problem vid amningsetablering. Ingen systematisk översikt har identifierats som undersökt effekten av tidig användning av napp på amningsetablering. Upplysningstjänsten har identifierat 13 primärstudier där sambandet mellan nappintroduktion under de första levnadsveckorna och amning under etableringsfas upp till de första tre månaderna var en av de aspekter som analyserats. Av dessa är elva studier observationsstudier, där studiedesignen gör det svårt att fastslå om det rör sig om orsakssamband mellan tidig nappintroduktion och amningsetablering. Amningsetableringen kan ha påverkats av andra faktorer än introduktion av napp.

Primärstudier granskas inte med avseende på risk för bias av Upplysningstjänsten så inga resultat eller slutsatser har redovisats i svaret, men studierna finns i tabellform i Bilaga 3 för den som önskar läsa mer.

På SBU:s upplysningstjänst identifierar och redovisar vi sammanställd forskning (systematiska översikter) eller identifierar vetenskapliga studier som svar på en avgränsad fråga. Vi bedömer risken för bias (överskattning eller underskattning av resultat) i systematiska översikter och presenterar författarnas slutsatser från systematiska översikter med låg eller måttlig risk för bias. I vetenskapliga primärstudier bedömer vi inte risken för bias och därför presenteras de bara som referenser. Vid behov bedömer vi kvalitet avseende ekonomiska aspekter och överförbarhet av resultat i hälsoekonomiska studier och presenterar författarnas slutsatser från de studier som bedöms ha minst medelhög kvalitet och överförbarhet. I svaren väger vi inte samman resultaten eller bedömer graden av vetenskaplig tillförlitlighet.

Bakgrund

Bröstmjölken innehåller den näring som behövs för spädbarn och ger ett visst skydd mot infektionssjukdomar [1]. År 2018 ammades 94 procent av barnen i Sverige vid en veckas ålder och 83 procent vid två månaders ålder [2]. WHO rekommenderar att amning inleds under den första levnadstimmen och upprätthålls under minst 6 månader [3].

Napp används för att tillfredsställa sugreflexen hos små barn och kan trösta och lugna barnen, framför allt vid insomning. Det finns en misstanke att tidig introduktion av napp, när introduktionen sker under de första levnadsveckorna, skulle kunna störa etablering av amningen. Orsaker skulle exempelvis kunna vara att det försvårar för föräldrarna att avläsa och svara på barnens amningssignaler, skapar förvirring kring sugteknik hos barnet eller stör mjölkproduktionen om barnet suger mindre vid bröstet.

Detta svar har tagits fram efter förfrågan från Socialstyrelsen i samband med arbetet med att uppdatera den gällande översättningen ”10 steg som främjar amning” från 2014 [4]. SBU:s upplysningstjänst publicerar två svar på denna fråga, detta svar samt svaret ”Napp mot plötslig spädbarnsdöd”.

Avgränsningar

Vi har gjort sökningar i databaserna i databaserna MedLine (Ovid), Embase, CINAHL och Scopus (se Bilaga 1).

Vi har formulerat frågan enligt följande PICO1:

För att vi skulle inkludera en artikel i svaret krävde vi att den var publicerad på engelska eller ett av de skandinaviska språken.

1. PICO är ett sätt att strukturera upp en frågeställning för att underlätta sökning och granskning. PICO är en förkortning för patient/population/problem, intervention/index test, comparison/control (jämförelseintervention) och outcome (utfallsmått).

Bedömning av risk för bias

Primärstudier bedöms inte för risk för bias av SBU:s upplysningstjänst eftersom det ställer krav på sakkunskap inom forskningsområdet. Det är därför möjligt att flera av studierna kan ha haft högre risk för bias än de studier som SBU inkluderar i andra rapporter.

Resultat från sökningen

Upplysningstjänstens litteratursökning genererade totalt 929 artikelsammanfattningar (abstrakt) efter dubblettkontroll. Ett flödesschema för urvalsprocessen visas i Bilaga 2. Två utredare på SBU läste alla artikelsammanfattningar och bedömde att 91 kunde vara relevanta. Dessa artiklar lästes i fulltext av två utredare och de artiklar som inte var relevanta för frågan exkluderades. Exkluderade artiklar finns listade i Bilaga 4.

Upplysningstjänsten identifierade ingen översikt som var relevant för frågan. 13 primärstudier bedömdes som relevanta och inkluderades.

Primärstudier

SBU:s upplysningstjänst identifierade 13 primärstudier [5–17], och dessa finns beskrivna i Bilaga 3. För primärstudier bedöms inte risken för bias och av det skälet finns inte resultat eller slutsatser beskrivna i text eller tabell.

Av de 13 inkluderade primärstudierna var 11 observationsstudier [5,6,8–16]. En svensk studie designades som en RCT, men analyserades även som en observationsstudie eftersom studiedeltagarna i de båda grupperna i hög grad avvek från den nappanvändning som föreskrevs i den studiegrupp de randomiserats till [7]. En äldre randomiserad studie jämförde en grupp där användning av alla sorters nappar och flaskor begränsades under BB-vistelsen med en grupp där nappar erbjöds alla barn och inga begränsningar kring flaskmatning gjordes [17].

Lästips

Fyra primärstudier motsvarade inte frågeställningen med avseende på tidpunkt för nappintroduktion eller uppföljningstid, men bedöms ändå vara intressanta.

I en svensk kohortstudie från år 2012 analyserade Almquist-Tangen och medarbetare vilka faktorer som inverkade på att amning upphörde under de första fyra levnadsveckorna [18].

Jakaité och medarbetare undersökte i en nyligen publicerad observationsstudie från år 2021 faktorer för helamning vid sex månader, bland annat tidig introduktion av napp [19].

Vogel och medarbetare fokuserar i en kohortstudie från år 2001 på hur nappanvändning påverkar flera olika amningsutfall [20].

En dansk observationsstudie från år 2009 av Kronborg och medarbetare undersökte nappanvändning och amningsteknik och dess påverkan på hur länge mödrarna ammade sina spädbarn [21].

Projektgrupp

Detta svar är sammanställt av Emma Palmqvist Wojda (utredare), Idha Kurtsdotter (utredare), Lisa Forsberg (utredare), Sara Fundell (projektadministratör), Irene Edebert (produktsamordnare), Per Lytsy (medicinskt sakkunnig) samt Pernilla Östlund (avdelningschef) vid SBU.

Referenser

  1. Livsmedelsverket. Bra mat för barn 0-5 år - handledning för barnhälsovård. Uppsala: Livsmedelsverket; 2013, version december 2020. [accessed Jun 21 2021]. Available from: https://www.livsmedelsverket.se/globalassets/publikationsdatabas/handbocker-verktyg/bra-mat-for-barn-0-5-ar---handledning-for-barnhalsovarden.pdf.
  2. Socialstyrelsen. Statistik om amning 2018. Stockholm: Socialstyrelsen; 2021. Artikelnummer 2021-5-7393. [accessed Jun 21 2021]. Available from: https://www.socialstyrelsen.se/globalassets/sharepoint-dokument/artikelkatalog/statistik/2021-5-7393.pdf.
  3. World Health Organization. Guideline: protecting, promoting and supporting breastfeeding in facilities providing maternity and newborn services: World Health Organization; 2017. License CC BY-NC-SA 3.0 IGO. [accessed Jun 21 2021]. Available from: https://apps.who.int/iris/bitstream/handle/10665/259386/9789241550086-eng.pdf?sequence=1&isAllowed=y.
  4. Socialstyrelsen. 10 steg som främjar amning. Stockholm: Socialstyrelsen; 2014. Artikelnr 2016-11-6. [accessed Jun 21 2021]. Available from: https://www.socialstyrelsen.se/globalassets/sharepoint-dokument/artikelkatalog/kunskapsstod/2014-10-27.pdf.
  5. Carbonell X, Botet F, Figueras J, Alvarez E, Riu A. The incidence of breastfeeding in our environment. J Perinat Med. 1998;26(4):320-4. Available from: https://doi.org/10.1515/jpme.1998.26.4.320.
  6. Declercq E, Labbok MH, Sakala C, O'Hara M. Hospital practices and women's likelihood of fulfilling their intention to exclusively breastfeed. Am J Public Health. 2009;99(5):929-35. Available from: https://doi.org/10.2105/AJPH.2008.135236.
  7. Hermanson A, Astrand LL. The effects of early pacifier use on breastfeeding: A randomised controlled trial. Women Birth. 2020;33(5):e473-e82. Available from: https://doi.org/10.1016/j.wombi.2019.10.001.
  8. Howard CR, Howard FM, Lanphear B, deBlieck EA, Eberly S, Lawrence RA. The effects of early pacifier use on breastfeeding duration. PEDIATRICS. 1999;103(3):E33. Available from: https://doi.org/10.1542/peds.103.3.e33.
  9. Ingram J, Johnson D, Greenwood R. Breastfeeding in Bristol: teaching good positioning, and support from fathers and families. Midwifery. 2002;18(2):87-101. Available from: https://doi.org/10.1054/midw.2002.0308.
  10. Kair LR, Colaizy TT. Association Between In-Hospital Pacifier Use and Breastfeeding Continuation and Exclusivity: Neonatal Intensive Care Unit Admission as a Possible Effect Modifier. Breastfeed Med. 2017;12:12-9. Available from: https://doi.org/10.1089/bfm.2016.0137.
  11. Kair LR, Kenron D, Etheredge K, Jaffe AC, Phillipi CA. Pacifier restriction and exclusive breastfeeding. PEDIATRICS. 2013;131(4):e1101-7. Available from: https://doi.org/10.1542/peds.2012-2203.
  12. Marques NM, Lira PI, Lima MC, da Silva NL, Filho MB, Huttly SR, et al. Breastfeeding and early weaning practices in northeast Brazil: a longitudinal study. PEDIATRICS. 2001;108(4):E66. Available from: https://doi.org/10.1542/peds.108.4.e66.
  13. Pineda R, Luong A, Ryckman J, Smith J. Pacifier use in newborns: related to socioeconomic status but not to early feeding performance. Acta Paediatr. 2018;107(5):806-10. Available from: https://doi.org/10.1111/apa.14253.
  14. Schliep KC, Denhalter D, Gren LH, Panushka KA, Singh TP, Varner MW. Factors in the Hospital Experience Associated with Postpartum Breastfeeding Success. Breastfeed Med. 2019;14(5):334-41. Available from: https://doi.org/10.1089/bfm.2018.0039.
  15. Sipsma HL, Kornfeind K, Kair LR. Pacifiers and Exclusive Breastfeeding: Does Risk for Postpartum Depression Modify the Association? J Hum Lact. 2017;33(4):692-700. Available from: https://doi.org/10.1177/0890334417725033.
  16. Huang YY, Lee JT, Gau ML, Huang CM. The study of pacifier use in relation to infant sucking, maternal perception of milk supply and breastfeeding duration. Macau Journal of Nursing. 2011;10(2).
  17. Schubiger G, Schwarz U, Tonz O. UNICEF/WHO baby-friendly hospital initiative: does the use of bottles and pacifiers in the neonatal nursery prevent successful breastfeeding? Neonatal Study Group. Eur J Pediatr. 1997;156(11):874-7. Available from: https://doi.org/10.1007/s004310050734.
  18. Almqvist-Tangen G, Bergman S, Dahlgren J, Roswall J, Alm B. Factors associated with discontinuation of breastfeeding before 1 month of age. Acta Paediatr. 2012;101(1):55-60. Available from: https://doi.org/10.1111/j.1651-2227.2011.02405.x.
  19. Jakaite V, Pestenyte A, Zakareviciene J, Snieckuviene V, Zitkute V, Ramasauskaite D, et al. Predictors of exclusive breastfeeding in the first six months: four consecutive surveys in a tertiary hospital in Lithuania. Int Breastfeed J. 2021;16(1):22. Available from: https://doi.org/10.1186/s13006-021-00364-6.
  20. Vogel AM, Hutchison BL, Mitchell EA. The impact of pacifier use on breastfeeding: a prospective cohort study. J Paediatr Child Health. 2001;37(1):58-63. Available from: https://doi.org/10.1046/j.1440-1754.2001.00581.x.
  21. Kronborg H, Vaeth M. How are effective breastfeeding technique and pacifier use related to breastfeeding problems and breastfeeding duration? Birth. 2009;36(1):34-42. Available from: https://doi.org/10.1111/j.1523-536X.2008.00293.x.

Bilaga 1 Litteratursökning

CINAHL via EBSCO 17 May 2021

Association between dummy use and breastfeeding

AB = Abstract; AU = Author; DE = Term from the thesaurus; MH= Exact Subject Heading from CINAHL Subject Headings; MM = Major Concept; TI = Title; TX = All Text. Performs a keyword search of all the database's searchable fields; ZC = Methodology Index; * = Truncation; “ “ = Citation Marks; searches for an exact phrase; N = Near Operator (N) finds the words if they are a maximum of x words apart from one another, regardless of the order in which they appear.; W = Within Operator (W) finds the words if they are within x words of one another, in the order in which you entered them.
  Search terms Items found
Population
1. TI ( newborn OR neonate* OR infant* ) OR AB ( newborn OR neonate* OR infant* ) OR SU ( newborn OR neonate* OR infant* ) 319 040
Intervention/Exposure
2. TI ( pacifier* OR comforter* OR soother* OR dummy OR dummies OR (non N1 nutri* N1 sucking) ) OR AB ( pacifier* OR comforter* OR soother* OR dummy OR dummies OR (non N1 nutri* N1 sucking) ) OR SU ( pacifier* OR comforter* OR soother* OR dummy OR dummies OR (non N1 nutri* N1 sucking) ) 2 644
Outcome
3. TI ( breastfeed* OR ‘breast feed*’ OR breastfed OR ‘breast fed’ OR wean* OR lactat* OR (nurs* N1 (newborn OR infant* OR mother*)) ) OR AB ( breastfeed* OR ‘breast feed*’ OR breastfed OR ‘breast fed’ OR wean* OR lactat* OR (nurs* N1 (newborn OR infant* OR mother*)) ) OR SU ( breastfeed* OR ‘breast feed*’ OR breastfed OR ‘breast fed’ OR wean* OR lactat* OR (nurs* N1 (newborn OR infant* OR mother*)) ) 59 353
Combined sets
4. 1 AND 2 AND 3 381
Limits
5. Academic journals  
Final result
  4 AND 5 333

Embase via Elsevier 17 May 2021

Association between dummy use and breastfeeding

/de = Term from the EMTREE controlled vocabulary; /exp = Includes terms found below this term in the EMTREE hierarchy; /mj = Major Topic; :ab = Abstract; :au = Author; :ti = Article Title; :ti,ab = Title or abstract; * = Truncation; ' ' = Citation Marks; searches for an exact phrase; NEAR/n = Requests terms that are within 'n' words of each other in either direction; NEXT/n = Requests terms that are within 'n' words of each other in the order specified
  Search terms Items found
Population
1. ’newborn’/exp 618 595
2. (newborn OR neonate* OR infant*):ti,ab,kw 715 116
3. 1 OR 2 1 063 443
Intervention/Exposure
4. ‘pacifier’/exp 908
5. (pacifier* OR comforter* OR soother* OR dummy OR dummies OR (non NEAR/2 nutri* NEAR/2 sucking)):ti,ab.kw 9 912
6. 4 OR 5 10 103
Outcome
7. ‘breast feeding’/exp OR ‘breast milk’/exp OR ‘lactation’/exp 126 809
8. (breastfeed* OR ‘breast feed*’ OR breastfed OR ‘breast fed’ OR wean* OR lactat*):ti,ab,kw 62 628
9. (nurs* NEAR/2 (newborn OR infant* OR mother*)):ti,ab,kw 4 725
10. 7 OR 8 OR 9 143 191
Limits:
11. (‘article’/it OR ‘article in press’ OR ‘review’/it)  
Combined sets
12. 3 AND 6 AND 10 651
Final result
  11 AND 12 539

Medline via OvidSP 17 May 2021

Association between dummy use and breastfeeding

.ab. = Abstract; .ab,ti. = Abstract or title; .af. = All fields; Exp = Term from the Medline controlled vocabulary, including terms found below this term in the MeSH hierarchy; .sh. = Term from the Medline controlled vocabulary; .ti. = Title; / = Term from the Medline controlled vocabulary, but does not include terms found below this term in the MeSH hierarchy; * = Focus (if found in front of a MeSH-term); * or $ = Truncation (if found at the end of a free text term); .mp = Text, heading word, subject area node, title; “ “ = Citation Marks; searches for an exact phrase; ADJn = Positional operator that lets you retrieve records that contain your terms (in any order) within a specified number (n) of words of each other.
  Search terms Items found
Population
1. infant, newborn/ 619 168
2. (newborn or infant* or neonat*).ab,kf,ti. 724 224
3. 1 or 2 1 036 640
Intervention/Exposure
4. Pacifiers/ 501
5. (pacifier* or soother* or comforter* or dummy or dummies or (non adj1 nutriti* adj1 sucking)).ab,kf,ti. 7 410
6. 4 or 5  
Outcome
7. Breast Feeding/ or Lactation/ or Lactation Disorders/ 79 612
8. (breastfeed* or breast feed* or breastfed or breast fed or wean* or lactat*).ab,kf,ti. 211 289
9. (nurs* adj2 (newborn or infant* or mother*)).ab,kf,ti. 4 848
10. 7 or 8 or 9  
Combined sets
11. 3 and 6 and 10 529
Final result
    529

Scopus via Elsevier 17 May 2021

Association between dummy use and breastfeeding

TITLE-ABS-KEY = Title or abstract or keywords; ALL = All fields; PRE/n = "precedes by". The first term in the search must precede the second by a specified number of terms (n).; W/n = "Within". The terms in the search must be within a specified number of terms (n) in any order.; * = Truncation; “ “ = Citation Marks; searches for an exact phrase; LIMIT-TO (SRCTYPE, "j" = Limit to source type journal; LIMIT-TO (DOCTYPE, "ar" = Limit to document type article; LIMIT-TO (DOCTYPE, "re" = Limit to document  type review
  Search terms Items found
Population
1. TITLE-ABS-KEY(infant OR newborn OR neonate) 1 651 439
Intervention/Exposure
2. TITLE-ABS-KEY(pacifier or dummy or comforter or soother or (non W/1 nutri* W/1 sucking)) 24 419
Outcome: Breast feeding
3. TITLE-ABS-KEY(breastfeed* OR “breast feed*” OR breastfed OR “breast fed” OR wean* OR lactat* OR (nurs* W/1 (newborn OR infant OR baby OR mother)) 397 754
Combined sets
4. 1 AND 2 AND 3 753
Limits:
5. Limit to: article, review, letter  
Final result
  4 AND 5 711

Bilaga 2 Flödesschema för urval av studier

Flödesschema för urval av studier. Började att granska 929 abstrakt från databassökning och slutade med att 0 systematiska översikter och 13 primärstudier inkluderarades

Bilaga 3 Inkluderade primärstudier

Included studies/ setting Population/ Exposure Measured outcome
Carbonell X et al, 1998
The incidence of breastfeeding in our environment. [5]
Study type: Observational

Setting: Barcelona, Spain
Maternity clinic in hospital
Population:
329 mothers and infants born during the study period

Exposure:
Early pacifier, during the first days of life
Measured outcome of interest: Breastfeeding at 3 months
Declercq E et al, 2009
Hospital practices and women's likelihood of fulfilling their intention to exclusively breastfeed. [6]
Study type: National survey (Listening to Mothers II)

Setting: USA
Population: 915 women aged 18 to 45 years who had given birth in 2005 in a hospital to a singleton, still-living infant and were non-Hispanic Black or Hispanic

Exposure: Hospital practice – the baby was given a pacifier in the hospital
Measured outcome of interest: Exclusive breastfeeding at 1 week, stratified by parity
Hermanson Å et al, 2020
The effects of early pacifier use on breastfeeding: A randomised controlled trial. [7]
Study type: Designed as RCT, also analysed on exposure as an observation study.

Setting: Sweden, Linköping University hospital
Population: 239 mother-infant pairs. Mothers were primiparous; intended to breastfeed their infants for at least four months and gave birth to healthy full-term infants (>37 weeks of gestation, birth weight >2500 g).

Intervention: Recommendation to offer a pacifier to their newborn child from the first day of life.

Control:
Recommendation to avoid pacifier to their newborn child during the first two weeks.
Measured outcome of interest: Exclusive and partial breastfeeding at 2 months

Primary outcome: Full and partial breastfeeding at 6 months
Howard CR et al, 1999
The effects of early pacifier use on breastfeeding duration. [8]
Study type: Prospective cohort
Data from a larger RCT

Setting: USA
Three independent, obstetric practices in six clinical offices in and around the Greater Rochester, NY, area.
Population: 265 breastfeeding mother–infant dyads

Exposure of interest:
Measured outcome of interest: Breastfeeding at 2 and 3 months
Huang YY et al, 2011
The study of pacifier use in relation to infant sucking, maternal perception of milk supply and breastfeeding duration. [16]
Study type: Longitudinal

Setting:
Taiwan
Population: 241 mother-infant pairs

Exposure of interest: Pacifier use at day 3 and at 2 weeks after birth
Measured outcome of interest: Infant sucking technique
Exclusive breastfeeding at 3 days and two weeks
Ingram J et al, 2002
Breastfeeding in Bristol: teaching good positioning, and support from fathers and families. [9]
Study type: Non-randomised prospective cohort

Setting: One postnatal hospital ward.
Population: 1325 mothers that were breastfeeding

Exposure: Dummy by 2 weeks
Measured outcome of interest: Any breastfeeding at 2 weeks
Kair LR et al, 2013
Pacifier restriction and exclusive breastfeeding. [11]
Study type: Retrospective before and after study

Setting: USA
Population: 2249 infants admitted to the mother-baby unit at a university teaching hospital

Exposure: Hospital practice – restricted routine pacifier distribution
Measured outcome of interest: Exclusive breastfeeding in the hospital
Exclusive formula-feeding in the hospital
Kair LR et al, 2017
Association Between In-Hospital Pacifier Use and Breastfeeding Continuation and Exclusivity: Neonatal Intensive Care Unit Admission as a Possible Effect Modifier. [10]
Study type: Cross-sectional survey
CDC Pregnancy Risk
Assessment Monitoring System (PRAMS)
Survey at 4 months postpartum

Setting: USA, 10 states
Population: 37628 mothers who were chosen by random birth certificate sampling

Exposure: Pacifier use during the birth hospitalization
Measured outcome of interest: Exclusive breastfeeding ≥10 weeks
Any breastfeeding ≥10 weeks
Marques NM et al, 2001
Breastfeeding and early weaning practices in northeast Brazil: a longitudinal study. [12]
Study type: Observational

Setting: Hospitals, multicentre, Pernambuco state, Brazil
Population: Mothers of infants with a birth weight of >2500 g (n=364)

Exposure of interest:: Pacifier introduction ≥7 days of age.
Measured outcome of interest: Introduction of other milk in first month of life
Pineda R et al, 2018
Pacifier use in newborns: related to socioeconomic status but not to early feeding performance. [13]
Study type: Observational; survey and feeding assessment

Setting: Single hospital, United States
Population: Mother-infant dyads (n=51). Infants born >37 weeks of gestation.

Exposure: Pacifier use at hospital.
Measured outcome of interest: Exclusively breastfed at hospital
Schliep KC et al, 2019
Factors in the Hospital Experience Associated with Postpartum Breastfeeding Success. [14]
Study type: Survey, Utah Pregnancy Risk Assessment Monitoring System (UT PRAMS)

Setting: Hospitals, multicentre, Utah, United States
Population: Mothers who gave birth in hospital (n=5501)

Exposure of interest: Pacifier given by hospital staff
Measured outcome of interest: Breastfeeding <2 months
Schubiger G et al, 1997
UNICEF/WHO baby-friendly hospital initiative: does the use of bottles and pacifiers in the neonatal nursery prevent successful breastfeeding? [17]
Study type: Multicentre prospective randomized trial.

Setting: Maternity services at 10 hospitals, Switzerland. Included hospitals had established functioning breastfeeding programmes with early initiation of breastfeeding, lactation consultants, unrestricted rooming-in and policy of restricted infant formula use
Population: 602 healthy newborns >37 weeks of gestation with mothers intending to stay at hospital for 5 days postpartum and planning to breast-feed for ≥3 months.

Intervention/control:UNICEF group [adhering to step six and nine in Baby-friendly hospital initiative]: Bottles, teats and pacifiers strictly forbidden; supplements, administered by cup or spoon, only given if medically indicated.
Standard group: Pacifiers offered to all infants without restriction; supplements conventionally offered by bottle after breastfeeding.
Measured outcome of interest: Breastfeeding at day 5 and 2 months.
Sipsma HL et al, 2017
Pacifiers and Exclusive Breastfeeding: Does Risk for Postpartum Depression Modify the Association? [15]
Study type:: National survey

Setting: Hospitals, multicentre, United States
Population: Mothers of healthy singleton babies >37 weeks of gestation, planning to breastfeed exclusively or in combination with formula (n=1349)
High risk for postpartum depression: 6.7% (n=91)
Lower risk for postpartum depression: 93.3% (n=1258)

Exposure: Receiving pacifier in hospital
Measured outcome of interest: Exclusive breastfeeding at one week
Exclusive breastfeeding at three weeks

Bilaga 4 Exkluderade studier

Exkluderade studier Kommentar
Systematiska översikter
Nasjonalt kunnskapssenter for helsetjenesten. Samsoving, smokk, amming og krybbedød – finnes det en sammenheng? 2005. Fel napp-exponering och amningsutfall
Buccini GDS, Pérez-Escamilla R, Paulino LM, Araújo CL, Venancio SI. Pacifier use and interruption of exclusive breastfeeding: Systematic review and meta-analysis. Matern Child Nutr. 2017;13(3). Available from: https://doi.org/10.1111/mcn.12384. Fel napp-exponering och amningsutfall
Callaghan A, Kendall G, Lock C, Mahony A, Payne J, Verrier L. Association between pacifier use and breast-feeding, sudden infant death syndrome, infection and dental malocclusion. Int J Evid Based Healthc. 2005;3(6):147-67. Available from: https://doi.org/10.1111/j.1479-6988.2005.00024.x. Fel napp-exponering och amningsutfall
Hewitt K, Binns C, Scott J, Forbes D. Pacifier use, breastfeeding and sudden infant death syndrome. Curr Pediatr Rev. 2012;8(4):285-91. Available from: https://doi.org/10.2174/157339612803307697. Fel napp-exponering och amningsutfall
Jaafar SH, Ho JJ, Jahanfar S, Angolkar M. Effect of restricted pacifier use in breastfeeding term infants for increasing duration of breastfeeding. Cochrane Database Syst Rev. 2016;2016(8). Available from: https://doi.org/10.1002/14651858.CD007202.pub4. Fel napp-exponering och amningsutfall
Jaafar SH, Jahanfar S, Angolkar M, Ho JJ. Pacifier use versus no pacifier use in breastfeeding term infants for increasing duration of breastfeeding. The Cochrane database of systematic reviews. 2011(3):CD007202. Available from: https://doi.org/https://dx.doi.org/10.1002/14651858.CD007202.pub2. Uppdaterad I Jaafar 2016
Jaafar SH, Jahanfar S, Angolkar M, Ho JJ. Pacifier use versus no pacifier use in breastfeeding term infants for increasing duration of breastfeeding. Cochrane Database Syst Rev. 2011(3):CD007202. Available from: https://doi.org/10.1002/14651858.CD007202.pub2. Uppdaterad I Jaafar 2016
Jaafar SH, Jahanfar S, Angolkar M, Ho JJ. Pacifier use versus no pacifier use in breastfeeding term infants for increasing duration of breastfeeding. Evid Based Child Health. 2012;7(3):1157-79. Available from: https://doi.org/10.1002/ebch.1853. Parallellpublikation till Jaafar 2012 som uppdateras i Jaafar 2016
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Jenik AG, Vain NE, Gorestein AN, Jacobi NE. Does the Recommendation to Use a Pacifier Influence the Prevalence of Breastfeeding? J Pediatr. 2009;155(3):350-4.e1. Available from: https://doi.org/10.1016/j.jpeds.2009.03.038. Fel napp-exponering
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