The systematic review showed the following graded results:
Limited scientific evidence (low quality evidence) represents a combined assessment of studies of high or moderate quality which disclose factors that markedly weaken the evidence. It is important to note that limited scientific evidence for the reliability of a method or an effect does not imply complete lack of scientific support.
Insufficient scientific evidence (very low quality evidence) represents either a lack of studies, or situations when available studies are of low quality or show contradictory results.
Evaluation of the evidence was not based on formal grading of the evidence according to GRADE but on an evaluation of the total scientific basis.
1 Three components of a whole. The triad associated with SBS usually comprises subdural hematoma, retinal hemorrhages and encephalopathy.
presents a comprehensive, systematic assessment of available scientific evidence. The certainty of the evidence for each finding is systematically reviewed and graded. Full assessments include economic, social, and ethical impact analyses.
SBU assessments are performed by a team of leading professional practitioners and academics, patient/user representatives and SBU staff. Prior to approval and publication, assessments are reviewed by independent experts, SBU’s Scientific Advisory Committees and Board of Directors.