http://www.sbu.se/ Some description..... EN http://www.sbu.se/en/Ongoing-projects/Antibiotic-prophylaxis-in-surgical-interventions/ Background Prophylaxis with general antibiotics is used in connection with certain surgical interventions to avoid bacterial endocarditis and prevent postoperative wound infections. Purpose The purpose of the project is to examine the scientific evidence for the effect of antibiotic prophylaxis on the occurrence of endocarditis and local or general infections after surgical interventions. We... SBU Monday, 19 Nov 2007 15:15:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Bleeding-Gastric-Ulcer/ Background Acute bleeding in the upper gastrointestinal tract is a life-threatening condition. The most common causes are gastric ulcer and oesophageal varices. Bleeding ulcer is the cause in most people age 65 and over. That is also the age group in which bleeding is most serious and leads to the greatest number of deaths. Among the risk factors are presence of the Helicobacter pylori bacterium,... SBU Monday, 12 Jan 2009 14:10:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Blood-test-for-early-diagnosis-of-Alzheimers-Disease/ Background There is ongoing research in the area of developing pharmaceuticals for Alzheimer’s Disease. Several new drugs are currently being tested on patients. If these trials are to show favourable results the need for a method to diagnose Alzheimer’s Disease at an early stage arises, as potential treatments need to be initiated in the early stages of the disease, in order to reach an optimal... SBU Wednesday, 23 Jun 2010 10:34:00 +02:00 http://www.sbu.se/en/Ongoing-projects/Catheter-ablation-of-atrial-fibrillation-update/ This project updates the SBU Alert report Catheter Ablation of Atrial Fibrillation » from 2005. SBU Monday, 30 Nov 2009 13:52:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Diagnosis-of-mood-disorders/ Depressive syndromes are among the most common causes of ill health, premature death, loss of productivity and capacity for work. The syndromes include depression, mania, dysthymia and combinations of these.  The diagnoses are made using the criteria in an American (DSM) or a European (ICD-10) classification system. Assessment is usually based on an interview with the patient, often with the aid... SBU Monday, 1 Feb 2010 12:50:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Diagnosis-and-treatment-of-ADHD-and-autism-spectrum-disorders/ Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASDs:  Aspergers Syndrome, autism and atypical autism) are conditions which should not be denoted primarily as diseases but more correctly as disabilities which make their debut in childhood. In a typical case, the afflicted individual has pronounced and sometimes very gravely compromised function, which effects the... SBU Monday, 1 Feb 2010 12:54:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Drug-eluting-stents-in-coronary-arteries-update/ This project updates the SBU Alert report Drug eluting stents in coronary arteries » from 2004. SBU Thursday, 1 Jul 2010 09:33:00 +02:00 http://www.sbu.se/en/Ongoing-projects/Home-Blood-Pressure-Monitoring/ Method and target group In Sweden, an estimated 1.8 million people have hypertension (high blood pressure). This corresponds to 27% of the adult population. Hypertension is treated through drugs and lifestyle modifications aimed at reducing the incidence of primarily stroke, but also myocardial infarction. In recent years it has become more common for patients to measure their own blood... SBU Wednesday, 13 Jan 2010 09:16:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Kyphoplasty-and-vertebroplasty-in-severe-back-pain-from-vertebral-compression-fractures/ Method and target group Vertebral compression involves the collapse of a vertebra, thereby reducing its height. Osteoporosis causes most of the approximately 15 000 vertebral compressions reported annually in Sweden. Other causes include myeloma or cancers with vertebral metastases. In percutaneous kyphoplasty (PKP), two orthopedic balloons are inflated in a compressed vertebra to restore... SBU Tuesday, 19 Feb 2008 09:39:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Diagnosis-and-treatment-of-psychosis-and-schizophrenia/ The estimated incidence of psychosis in the population is 0.5–0.7 percent. Psychosis is characterised by a changed perception of reality and diminished functional ability which often leads to deterioration in social support. Of the psychotic diseases, the most serious diagnosis is schizophrenia.  Men are usually afflicted earlier in life than women. The diagnosis is based on clinical evaluation... SBU Monday, 1 Feb 2010 12:54:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Methods-of-diagnosing-and-treating-diseases-of-the-dental-pulp-and-the-periradicular-tissues-around-the-root/ BackgroundEndodontics is the field of dentistry dealing with the study, treatment and prevention of diseases of the dental pulp, and pathological processes originating in pulpal tissue. The pulp may be damaged in various ways. Among the common causes are deep caries, cracks, dental fillings and trauma to the teeth. The first stage is inflammation of the pulp, which is sometimes very painful and... SBU Wednesday, 10 Dec 2008 14:06:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Methods-of-preventing-mental-ill-health-among-schoolchildren/ Background Mental ill-health is one of the most serious health problems among Swedish children and adolescents. Various surveys suggest that 10-25 percent of children have mental problems so severe that they or those around them suffer. Mental ill-health includes acting-out behaviour, depression, anxiety, impaired cognitive development and other conditions. There are many factors that can... SBU Friday, 5 Dec 2008 13:55:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Noninvasive-Prenatal-Diagnosis--Analyses-of-Fetal-DNA-in-Maternal-Blood/ Background The concept of prenatal diagnostics applies both to screening offered to all pregnant women and also to diagnostic examinations offered to selected groups of pregnant women. Several different methods for early fetal diagnosis have been assessed within the framework of previous SBU projects. A new noninvasive method (noninvasive prenatal diagnosis – NIPD) uses free fetal DNA in... SBU Friday, 11 Jun 2010 09:48:00 +02:00 http://www.sbu.se/en/Ongoing-projects/Prosthetic-treatment-of-missing-teeth/ BackgroundOral health plays a major role in our perception of wellbeing and quality of life. Having a mouth marred by visible gaps due to missing teeth can be a social stigma. Loss of teeth can make it difficult to engage in activities such as talking, articulating properly, laughing or playing wind instruments. There is also loss of masticatory function, eventually giving rise to digestive... SBU Wednesday, 10 Dec 2008 14:04:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Symptomatic-benign-prostatic-obstruction-BPO/ BackgroundSymptomatic benign prostatic obstruction (BPO) is an age-related disease. Benign prostatic hyperplasia (BPH), on the other hand, does not necessarily imply the existence of symptoms or obstruction. Approximately 50 percent of men at age 60 and 90 percent of men at age 80 have BPH. Half of them have moderate to severe symptoms. The total cost of medications for BPH among Swedish men has... SBU Friday, 30 Jan 2009 11:04:00 +01:00 http://www.sbu.se/en/Ongoing-projects/The-impact-of-the-work-environment-on-musculoskeletal-diseases--a-systematic-review-of-the-literature/ Background Medical researchers hold varying opinions concerning the impact of the work environment on musculoskeletal diseases. No up-to-date, scientifically based compilation of research in this field is currently available. Thus, there is a great need for a compilation of the research that has been conducted about the impact of the work environment on musculoskeletal diseases. Many people... SBU Thursday, 22 Jan 2009 10:59:00 +01:00 http://www.sbu.se/en/Ongoing-projects/Urine-Tests-in-Diagnosing-Chlamydia-in-Women/ Method and target group Chlamydia is a notifiable disease and the most commonly reported sexually transmitted disease in Sweden. The number of reported cases has increased every year since 1997. A bacterium (Chlamydia trachomatis) causes the disease and can be found in the urethra, vagina, rectum, throat, or eyes. Transmission occurs through unprotected sexual contact. Many of those infected do... SBU Friday, 15 Jan 2010 12:34:00 +01:00